Our Wellness 360° Tests
Our Blood Tests
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Biomarkers Analysed:
Liver Function: ALT, ALP, GGT, Bilirubin, Albumin, Globulin, Total Protein
Kidney/U&E: Creatinine, Urea, Uric Acid
Lipids: HDL, LDL, Total Cholesterol, Triglycerides, Omega 6:3
Iron Studies: Iron, Ferritin, TIBC, Transferrin Saturation
Thyroid: TSH, FT4, FT3, T4, Anti-Tg Abs, Anti-TPO Abs
Sex/Reproductive Hormones: Oestradiol, Progesterone, Testosterone, Free T, SHBG, LH, FSH, Prolactin
Adrenal: Cortisol, DHEA-S
Haematology: HbA1c, RBC, WBC, Platelets, Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils, HCT, MCV, MCH, MCHC, RDW-CV, MPV
Nutrition: Vitamin D, B12, Folate, Magnesium, Zinc, Copper
Other: α-Amylase, PSA for men
Clinical Use
The Wellness 360 panel offers a comprehensive overview of key physiological systems, helping to identify underlying imbalances that may contribute to a wide range of symptoms. It is particularly useful for investigating concerns such as:
Shifts in energy levels or persistent fatigue
Frequent infections or reduced immune resilience
Blood sugar dysregulation and insulin resistance
Signs of anaemia or nutrient depletion
Digestive issues, including loose stools or poor absorption
Vitamin and mineral imbalances (deficiencies or excesses)
Changes in sleep quality or circadian rhythm disruption
Hormonal fluctuations and mood disturbances
With its broad scope, Wellness 360 is ideal for both baseline health screening and targeted investigation in patients presenting with complex or non-specific symptoms.
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Biomarkers Analysed:
Kidney Function: Creatinine with eGFR, Cystatin C
Lipids: HDL, LDL (calculated), Total Cholesterol, Triglycerides, VLDL (calculated), Non-HDL Cholesterol (calculated)
Glucose/Insulin Regulation: Glucose, Insulin, Glycomark (1,5-AG)
Adipokines & Metabolic Health: Adiponectin, Leptin, Leptin : Adiponectin Ratio
Cardiovascular Risk Markers: Apo A1, Apo B, Lipoprotein (a), Oxidised LDL, Small dense LDL (calculated), hsCRP, Homocysteine
Clinical Use
This advanced cardiovascular and metabolic panel provides a detailed assessment of cardiovascular disease (CVD) riskand metabolic health. It goes beyond standard lipid testing by evaluating atherogenic lipoprotein subtypes, apolipoproteins, arterial inflammation markers, and lipoprotein-associated phospholipase A2 (PLAC®) activity. This allows for the early detection of active atherogenesis, plaque vulnerability, and underlying metabolic dysfunction linked to metabolic syndrome and type 2 diabetes.
When to Consider This Test
Ideal for patients with:
A personal or family history of cardiovascular disease
Central or abdominal weight gain
Obesity or elevated BMI
Insulin resistance or prediabetes
Non-alcoholic fatty liver disease (NAFLD)
This test is particularly valuable for individuals seeking preventive, personalised strategies to reduce long-term cardiovascular and metabolic risk.
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Biomarkers Analysed:
Macrominerals (Serum/Whole Blood):
Calcium (Serum), Calcium (Whole Blood), Magnesium (Serum), Magnesium (Whole Blood), Phosphorus (Serum), Potassium (Serum), Sodium (Serum)Trace Minerals (Essential):
Copper, Iron (Serum), Zinc, Selenium, Manganese, Chromium, Molybdenum, CobaltToxic & Heavy Metals:
Arsenic, Barium, Cadmium, Lead, Mercury, Thallium, Uranium, Aluminium, Nickel, Vanadium, Platinum, Strontium, Tungsten, Lithium
Clinical Use
The Comprehensive Blood Elements Profile measures both whole blood and serum to provide a detailed analysis of essential and toxic elements.
Whole blood analysis is particularly valuable for detecting toxic metal exposure—such as lead, mercury, or arsenic—and reflects both recent and cumulative exposure.
Serum analysis evaluates essential elements and electrolytes vital for extracellular fluid balance, nerve function, and metabolic processes.
When to Consider This Test
This test is ideal for patients where there is clinical suspicion of:
Nutritional deficiencies (e.g., magnesium, zinc, copper)
Toxic element exposure (e.g., mercury, lead, arsenic)
Hypertension or cardiovascular disease
Mood disorders such as depression or anxiety
Fatigue, brain fog, or poor detoxification capacity
Whole blood testing offers insight into both intracellular and extracellular element status, making it a powerful tool for identifying hidden imbalances that may impact long-term health and well-being.
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Biomarkers Analysed:
Omega-3 Fatty Acids: EPA, DHA, DPA (Docosapentaenoic acid), ALA (Alpha-linolenic acid), Total Omega-3 Fatty Acids
Omega-6 Fatty Acids: LA (Linoleic Acid), GLA (Gamma-linolenic Acid), EDA (Eicosadienoic Acid), DGLA (Dihomo-γ-linolenic Acid), AA (Arachidonic Acid), DTA (Docosatetraenoic Acid), DPA-n6 (Docosapentaene-n6), Total Omega-6 Fatty Acids
Omega-9 Fatty Acids: Oleic Acid, Gadoleic Acid, Nervonic Acid, Total Omega-9 Fatty Acids
Saturated Fatty Acids: Myristic Acid, Palmitic Acid, Stearic Acid, Arachidic Acid, Behenic Acid, Lignoceric Acid, Total Saturated Fats
Trans Fatty Acids: Trans-palmitolein, Trans-oleic Acid, Trans-linoleic Acid, Total Trans Fats
Key Ratios: AA/EPA (Arachidonic : Eicosapentaenoic Ratio)
Clinical Use
The Fatty Acid Blood Spot Test provides a detailed analysis of your body’s fatty acid profile, including Omega-3, Omega-6, Omega-7, and saturated fats. At the core of this test is the High Sensitivity Omega-3 Index® (HS-Omega-3 Index®)—a scientifically validated marker that reflects long-term omega-3 status and its relationship to health outcomes.
Developed by Prof. Dr. W.S. Harris (Sanford University, USA) and Prof. Dr. C. von Schacky (Ludwig Maximilian University of Munich and founder of Omegametrix), the HS-Omega-3 Index® is considered the gold standard in fatty acid testing. With over 250 peer-reviewed studies and 50+ ongoing research projects worldwide, it is widely recognised in clinical practice and research.
The HS-Omega-3 Index® measures the percentage of EPA and DHA in red blood cell membranes—an optimal range is 8–12%, with 10% being ideal. This index has been strongly linked to improved cardiovascular, neurological, and general health outcomes.
When to Consider This Test
This test is recommended for individuals looking to optimise:
Cardiovascular health and recovery post-cardiac event
Mood and mental health, including support for depression and ADHD
Cognitive performance and mental agility
Pregnancy health, particularly for foetal brain, nerve, and eye development
Immune system function
General wellbeing and inflammation balance
It’s an essential tool for anyone interested in using nutrition to prevent disease, support recovery, or enhance long-term health through personalised, evidence-based supplementation.
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Biomarkers Analysed:
1-Methylhistidine
3-Methylhistidine
Alanine
𝛼-Amino-N-butyrate
𝛼-Aminoadipate
Ammonia
Anserine
Arginine
Asparagine
Asparagine : Aspartate Ratio
Aspartate
β-Alanine
β-Aminoisobutyrate
Carnosine
Citrulline
Cystathionine
Cysteine
Ethanolamine
Glutamate
Glutamine
Glutamine : Glutamate Ratio
Glycine
Histidine
Homocystine
Hydroxyproline
Isoleucine
Leucine
Lysine
Methionine
Methionine Sulfoxide
Ornithine
Phenylalanine
Phosphoethanolamine
Phosphoserine
Proline
Sarcosine
Serine
Taurine
Threonine
Tryptophan
Tyrosine
Urea
Valine
Gamma-Aminobutyric Acid (GABA)
Clinical Use
Amino acid testing provides valuable insight into dietary protein intake, amino acid balance, and overall nutritional adequacy. It plays a critical role in evaluating a range of health factors, including:
Gastrointestinal dysfunction
Protein intolerance or malabsorption
Vitamin and mineral deficiencies
Liver and kidney function
Neurotransmitter imbalances
Inflammatory and oxidative stress risk
Genetic or acquired disorders of amino acid metabolism
This comprehensive analysis helps identify both functional and metabolic imbalances, supporting personalised nutrition and targeted therapeutic interventions.
When to Consider This Test
This test is ideal when investigating:
Inadequate or imbalanced protein intake
Digestive disturbances affecting nutrient absorption
Chronic fatigue, mood changes, or cognitive concerns linked to neurotransmitter precursors
Detoxification challenges or increased oxidative stress
Suspected inherited or acquired amino acid metabolism disorders
Degenerative disease risk due to poor methylation, detox, or antioxidant pathways
Amino acid profiling offers a deeper understanding of how nutrition impacts biochemical function and is a powerful tool in functional, nutritional, and integrative medicine.
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Biomarkers Analysed:
Liver Function: ALT, AST, ALP, GGT, Total Bilirubin, Direct Bilirubin, Indirect Bilirubin, Albumin, Total Protein
Pancreatic Enzymes: Amylase, Lipase
Kidney/U&E: Creatinine, eGFR, Urea, Uric Acid, Sodium, Potassium, Chloride, Bicarbonate, Anion Gap (calculated), Phosphate
Lipid Profile: HDL, LDL (calculated), Total Cholesterol, Triglycerides, VLDL (calculated), Total Cholesterol : HDL Ratio
Thyroid Panel: TSH, FT4, FT3, T4, Reverse T3 (rT3), T3 Uptake, Thyroglobulin Antibodies (TgAb), Thyroid Peroxidase Antibodies (TPO)
Metabolic Markers: Glucose, Insulin, C-peptide, HbA1c, Homocysteine
Haematology: Haemoglobin (Hgb), RBC, WBC, Platelets, Reticulocytes, MCV, MCH, MCHC, RDW-CV, RDW-SD, MPV, PDW, Neutrophils, Lymphocytes, Monocytes, Eosinophils, Basophils
Inflammation & Immune Function: hsCRP, ESR, Fibrinogen, Procalcitonin (PCT), Immunoglobulin A (IgA), G (IgG), M (IgM)
Nutritional Markers: Vitamin B12, Active B12 (Holo-transcobalamin), Serum Folate, Vitamin D (25-OH), Iron, TIBC, UIBC, Transferrin Saturation, Magnesium, Copper, Selenium, Palladium
Other Functional Markers: Creatine Kinase (CK), Lactate Dehydrogenase (LDH)
Option to add sex hormones for additional cost
When to Consider This Test
The Platinum Plus Fx Blood Panel offers a comprehensive analysis of 83 key blood markers, covering essential areas such as haematology, biochemistry, endocrinology, and immunology. It provides an in-depth view of your internal health, helping to identify imbalances, deficiencies, or dysfunctions across multiple body systems.
This test is ideal for:
Baseline health screening or annual health check-ups
Patients with non-specific or complex symptoms
Monitoring of chronic conditions and treatment response
Identifying underlying factors contributing to fatigue, inflammation, hormonal imbalance, or immune dysfunction
Supporting personalised medicine and preventative care strategies
With its wide diagnostic scope, the Platinum Plus Fx panel is a valuable tool for both early detection and ongoing management of a wide range of health concerns.
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Food Inflammation Test
The KBMO FIT 176 is a cutting-edge food sensitivity test that measures both IgG antibody responses and complement (C3d) activation to 176 common foods and food additives. This dual-pathway approach goes beyond standard food intolerance testing by identifying not just immune reactivity, but inflammatory potential, helping to uncover hidden food triggers that may be contributing to:
Bloating, IBS, or digestive discomfort
Headaches or migraines
Fatigue and brain fog
Joint pain or skin issues
Mood changes or sleep disturbances
Unlike allergy testing, which detects immediate IgE reactions, the FIT 176 captures delayed immune responses — which can take hours or even days to manifest — making it a valuable tool for identifying subtle, chronic food-related inflammation.
The panel includes:
A wide range of foods: dairy, gluten-containing and gluten-free grains, fruits, vegetables, meats, seafood, nuts, seeds, herbs, spices, and beverages
Additives and preservatives such as food dyes, gums, and sweeteners
Candida and other yeast markers
You’ll receive:
A personalised report showing your reactivity to each tested item
A colour-coded guide for easy interpretation
A 7-day rotational meal plan based on your results
Optional follow-up consultation to support dietary changes and gut healing
The FIT 176 is ideal for those with chronic symptoms or those following a functional medicine approach to wellness.
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Multi-Cancer Early Detection Blood Test
Trucheck Intelli is an advanced, non-invasive blood test that enables the early detection of multiple cancers from a single blood draw — even before symptoms appear. Using cutting-edge circulating tumour cell (CTC) technology, Trucheck Intelli screens for the presence of 70+ types of solid organ cancers with remarkable accuracy.
Unlike traditional screening, which typically focuses on one type of cancer at a time (e.g., breast, colon, or prostate), Trucheck Intelli offers a broad-spectrum approach — making it a powerful tool for proactive health monitoring and peace of mind.
Key Features:
Screens for 70+ solid organ cancers, including lung, breast, pancreas, ovary, prostate, liver, and colon
Detects circulating tumour cells (CTCs) in the blood — a proven early marker of malignancy
Helps identify the tissue of origin if cancer cells are detected
Suitable for asymptomatic individuals, high-risk patients, or those with a family history of cancer
No radiation or invasive procedures required
Trucheck Intelli is ideal for individuals who value a preventive, proactive approach to health, especially when combined with personalised lifestyle and functional medicine support.
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Tests for: Almond, Apple, Asparagus, Aspergillus Mix, Avocado, Banana, Barley, Beef, Black Pepper, Blueberry, Brewers Yeast, Broccoli / Brussel Sprouts, Cabbage, Cacao, Candida, Cantaloupe, Carrot, Casein, Cashew, Cauliflower, Celery, Cherry, Chicken, Cinnamon, Clam, Coconut, Codfish, Coffee Bean, Corn, Cottonseed, Cow's Milk, Crab, Cucumber, Egg Albumin, Egg Yolk, English Walnut, Flax Seed, Flounder, Garlic, Ginger, Gluten IgG, Goat's Milk, Grapefruit, Grapes, Green Olive, Green Pea, Green Pepper, Halibut, Honeydew Melon, Hops, Kidney Bean, Lemon, Lettuce, Lima Bean, Lobster, Mushroom, Mustard, Navy Bean, Oat, Onion, Orange, Peach, Peanut, Pear, Pecan, Pineapple, Plum, Pork, Rice, Rye, Salmon, Scallops, Sesame Seed, Shrimp, Soybean, Spinach, Strawberry, String Bean, Sweet Potato, Tea, Tomato, Tuna, Turkey, Vanilla, Watermelon, White Potato, Whole Wheat, Yellow Squash
Clinical Use
The P88 Dietary Antigen Test offers a comprehensive evaluation of immune responses to 88 commonly consumed foods by measuring IgE, IgG, IgG4, and complement (C3d) activity.
IgE identifies immediate allergic reactions.
IgG detects delayed hypersensitivity responses.
IgG4 provides insight into immune tolerance.
Complement (C3d) activation highlights inflammatory reactions that may not be picked up through antibody testing alone.
By combining these markers, the test delivers a broad and sensitive overview of both food allergies and sensitivities, offering valuable guidance for dietary interventions and long-term symptom relief.
When to Consider This Test
Consider the P88 Dietary Antigen Test for individuals with:
Chronic inflammatory symptoms such as headaches, joint pain, fatigue, or skin issues
Digestive complaints, including bloating, IBS, or food intolerances
Suspected food-related immune activation contributing to chronic conditions
A need for a personalised elimination or rotational diet plan
This test is particularly useful in uncovering hidden dietary triggers that may contribute to autoimmune conditions, eczema, migraines, ADHD, and other chronic illnesses. It supports a targeted, evidence-based approach to dietary modification and functional medicine treatment planning.
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TruAge COMPLETE offers a comprehensive analysis of biological ageing through cutting-edge epigenetic algorithms and reports. Unlike chronological age, which simply reflects the number of years you've lived, biological age reveals how well your body is ageing on a cellular level—providing valuable insight into your overall health and risk of age-related diseases.This advanced test includes multiple scientifically validated ageing algorithms:
DunedinPACE – A pace-of-ageing measure based on physiological function and phenotypic ageing, rather than just time.
OMICm Age – Developed in collaboration with Harvard University, this algorithm identifies potential drivers of accelerated ageing, including inflammation and metabolic stress.
Additional insights include your fitness age, weight loss response, blood sugar control, inflammatory regulation, and more.
TruAge COMPLETE is ideal for individuals looking to track longevity, optimise healthspan, and tailor interventions to slow the ageing process through lifestyle, nutrition, and personalised health strategies.
Tested Biomarkers
12 Cell Immune Subsets
Average Telomere Length
Disease Risk Score - Type II Diabetes
DunedinPACE
Inflammation Report (DNAmCRP & DNAmIL-6)
Mitotic Clock
OMICm Biological Age
OMICm FitAge
Smoking & Drinking Report
SYMPHONYAge (11 organ systems)
Weight Loss Response Report
When to Consider This Test
TruAge COMPLETE is ideal for individuals who want a deep and personalised understanding of their biological age, healthspan potential, and the internal factors driving their ageing process. It is especially recommended for first-time users seeking to establish a comprehensive baseline of their current ageing status.
This test is particularly valuable for those interested in:
Tracking long-term health and disease risk
Preventing or reversing premature ageing
Personalising health, fitness, and lifestyle interventions
What You’ll Gain from This Test
Biological Age & Disease Risk – OMICm Age (developed with Harvard) uses advanced multi-omics analysis to uncover molecular drivers of ageing and offer targeted longevity recommendations.
Rate of Ageing – DunedinPACE measures your current pace of ageing, based on data from the world-renowned Dunedin Study.
Organ System Ageing – SYMPHONYAge (developed with Yale) evaluates ageing across 11 organ systems, providing a full-body biological clock estimate.
Additional Insights – Includes metrics such as fitness age, telomere length, immune cell profile, alcohol and tobacco impact, inflammatory control, and weight loss responsiveness.
Together, these insights provide a holistic view of how your body is ageing and empower you to take evidence-based steps toward extending your healthspan and improving quality of life.
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The TruHealth Test offers an advanced, holistic analysis of your functional, nutritional, and systemic health by evaluating over 110 epigenetic biomarker proxies.
Using cutting-edge DNA methylation technology, this test provides predictive insights into your biological function—offering a deeper view than traditional blood tests, which only reflect a single point in time. Epigenetic biomarkers reveal the long-term effects of nutrient status, metabolic processes, and overall biochemical balance.By assessing cellular health across key systems—including metabolic function, immune resilience, NAD⁺ metabolism, and neurocognitive performance—TruHealth can uncover underlying imbalances and potential deficiencies that may be affecting your well-being. The results offer personalised, data-driven guidance to support targeted nutrition, detoxification, sleep optimisation, and metabolic health strategies.
TruHealth is ideal for individuals seeking proactive, precision-based care to optimise long-term vitality and healthspan.
Tested biomarkers
Vitamins: Vitamin A, Vitamin B2, Vitamin B3, Vitamin B5, Vitamin B6, Vitamin B8 (Inositol), Myoinositol, Vitamin C, Vitamin D, Vitamin E, Choline, Betaine
Amino Acids & Metabolism: Methionine, Cysteine, S-methylmethionine, Taurine, Glutamine, Arginine, Tyrosine, L-Aspartic Acid, Valine, Asparagine, Threonine, Glycine, Carnosine, Histidine, Citrulline, Phenylalanine, Nicotinamide, Nicotinamide Riboside, 1-MNA (1-Methylnicotinamide), Creatine
Minerals: Iron (Transferrin), Magnesium, Potassium, Calcium, Copper (Ceruloplasmin)
Essential Fats & Lipids: Omega 3, DHA (Docosahexaenoate), DPA (Docosapentaenoic Acid), EPA (Eicosapentaenoate), Omega 6, LA, PUFA, PUFA%, MUFA, MUFA%, SFA, SFA%, Pentadecanoate, Phosphoglycerides, Phosphatidylcholine, Sphingomyelins, Phospholipase A2
Antioxidants & Detox: Carotenoids, Glutathione Peroxidase, Ergothioneine, Oxidative Stress Marker (Methionine Sulfone), Oxidative Stress Indicator (Methionine Sulfone), Oxidative Damage Indicator (Allantoin), Byproduct Marker (2PY – N1-Methyl-2-Pyridone-5-Carboxamide), Serum Amyloid A-1 Protein, Glycoprotein Acetyls
Cardiovascular & Lipoproteins: ApoB, LDL-C, LDL Particle Size, VLDL-C, VLDL Particle Size, ApoA1, HDL-C, HDL Particle Size, Triglycerides, HbA1c, Glucose, Systolic Blood Pressure
Energy & Mitochondrial Markers: Fat Burning Marker (Palmitoylcarnitine), Beta-Hydroxybutyrate (BHBA), Acetoacetate, Alpha-Ketoglutarate, Energy Balance Marker (DRP1 – Dynamin-1-Like Protein), ATP Synthase Subunit Beta (ATP5B), Electron Transfer Flavoprotein Subunit Alpha (ETFa), Spermidine, Palmitoyl Ethanolamide
Neurotransmitters & Cognitive Health: Vanilmandelic Acid (VMA), Dopamine Metabolites (Dopamine 3-O-Sulfate, Dopamine 4-Sulfate), Brain Inflammation Marker (Quinolinate), Memory Health Protein (Neurogranin), Brain Anti-Inflammatory Protein (Progranulin), Cell Repair Marker (TGF-Beta), IL-6
Immune & Inflammation Markers: CRP, White Blood Cell Count, Neutrophils, Lymphocytes, Neutrophil to Lymphocyte Ratio (NLR), Systemic Immune-Inflammation Index, CD4/CD8 Ratio, Myeloperoxidase (MPO)
Stress & Hormonal Markers: Cortisol, Adrenal Activity Marker (VMA), Chronic Stress Marker (Kynurenine)
Environmental Toxins & Exposure: PFAS (PFOS, PFOA), Acrolein (HPMA – S-(3-Hydroxypropyl)Mercapturic Acid), Polycyclic Aromatic Hydrocarbons (2-Hydroxyfluorene Sulfate), Pesticides (Glyphosate), Lead Exposure (Bone Lead Predictor)
Uric Acid & Purine Metabolism: Uric Acid, Xanthine, Hypoxanthine
When to Consider the TruHealth Test
TruHealth’s Epigenetic Biomarker Proxy (EBP) test offers a powerful tool for advanced health assessment through cutting-edge DNA methylation analysis. Ideal for any patient seeking personalised, preventive, or precision care, this test provides insights beyond traditional lab testing by evaluating over 1,600 clinically relevant proxies that mirror metabolic, proteomic, and biochemical health markers.
You may wish to consider this test for patients who:
Have complex or chronic health conditions requiring deeper insight
Are interested in optimising long-term health and disease prevention
Need more precise, personalised care planning
Want to assess the impact of lifestyle, nutrition, or environment on their health
Seek a comprehensive picture of systemic function across multiple organ systems
Why TruHealth?
Extensive Clinical Associations: Over 1,292 incident and 4,863 prevalent disease associations, often with greater predictive value than standard lab tests.
Exceptional Predictive Power: High sensitivity and specificity for disease trajectory, allowing early identification of key metabolic and inflammatory patterns.
Versatile Application: Validated in both healthy and clinical populations, EBPs provide insight into subtle dysfunction, early-stage imbalances, and long-term health trajectories.
Whether you're managing chronic disease, identifying at-risk individuals, or guiding proactive wellness plans, the TruHealth EBP test adds unparalleled depth to your clinical toolkit.
Our DNA Tests
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Our Urine Tests
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Biomarkers Analysed:
Oestrogen Metabolism:
Estrone (E1), Estradiol (E2), Estriol (E3), Total Oestrogen,
2-Hydroxyestrone (2-OH-E1), 2-Hydroxyestradiol (2-OH-E2),
4-Hydroxyestrone (4-OH-E1), 4-Hydroxyestradiol (4-OH-E2),
16-Hydroxyestrone (16-OH-E1), 2-Methoxyestrone (2-Me-E1),
Methylation Activity (2-Me-E1 / 2-OH-E1)Androgen Metabolism:
Testosterone, Epi-Testosterone,
Dihydrotestosterone (DHT), 5a-Dihydrotestosterone (5a-DHT),
5a-Androstanediol, 5b-Androstanediol,
Androsterone, EtiocholanoloneProgesterone & Corticosteroids:
Progesterone (calculated equivalent),
𝛼-Pregnanediol, β-Pregnanediol,
𝛼-Tetrahydrocortisol (a-THF),
β-Tetrahydrocortisol (b-THF), β-Tetrahydrocortisone (b-THE),
Metabolised Cortisol (THF + THE)Cortisol & Cortisone (Adrenal Function):
24hr Free Cortisol, 24hr Free Cortisone,
Cortisol (Saliva), Cortisone (Saliva)DHEA & Related Markers:
Dehydroepiandrosterone Sulfate (DHEA-S),
Total Dehydroepiandrosterone (DHEA)Neurotransmitter & Brain Health Markers:
Melatonin,
Homogentisic Homovanillic Acid (HVA),
Vanillylmandelic Acid (VMA),
5-Hydroxyindolacetate (5HIAA),
Quinolinate (Neuroinflammation marker),
XanthurenateDetoxification & Oxidative Stress:
8-Hydroxy-2'-deoxyguanosine (8-OHdG),
Indican,
Pyroglutamate,
Methylmalonic Acid (MMA),
β-Hydroxyisovalerate
Clinical Use
DUTCH Plus is a comprehensive hormone test that evaluates 35 sex and adrenal hormones, along with their key metabolites, to offer a detailed picture of hormonal balance and function. It uniquely measures the Cortisol Awakening Response (CAR) through saliva, providing crucial insights into HPA axis activity and stress resilience—something standard cortisol testing often misses.
In addition to sex and stress hormones, DUTCH Plus includes:
8-OHdG – a marker of oxidative DNA damage
Melatonin – assessing circadian rhythm and sleep regulation
9 organic acids, including indicators for:
Vitamin B levels
Glutathione (antioxidant status)
Dopamine and neurotransmitter metabolism
Neuroinflammation
This test uses a simple combination of dried urine and saliva samples, making it convenient and non-invasive while offering exceptionally rich clinical data.
When to Consider This Test
Consider DUTCH Plus for:
Hormonal imbalances (e.g. irregular cycles, PMS, perimenopause, low libido, PCOS, and andropause)
Adrenal dysfunction, fatigue, or chronic stress
Sleep disturbances or low melatonin levels
Mood changes, anxiety, or poor stress tolerance
Symptoms suggesting oxidative stress, detox issues, or neurotransmitter imbalance
It’s ideal for both men and women and supports personalised, root-cause treatment planning by linking hormone patterns with nutritional, neurological, and detoxification markers.
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Biomarkers analysed
Energy Production & Krebs Cycle Intermediates:
Citric, Aconitic, Succinic, Fumaric, Malic, Pyruvic, Oxoglutaric, 2-Oxoglutaric, 3-Oxoglutaric, Methylsuccinic, Lactic
Amino Acid & Protein Metabolism:
2-Hydroxyisocaproic, 2-Hydroxyisovaleric, 2-Oxoisocaproic, 2-Oxoisovaleric, 3-Methylglutaric, 3-Methylglutaconic, 3-Methyl-2-oxovaleric, Glutaric (Vitamin B2 – Riboflavin), Phenylpyruvic, Phenyllactic, Kynurenic, Quinolinic, N-Acetylaspartic, N-Acetylcysteine, Indoleacetic, 3-Indoleacetic, Homogentisic
Neurotransmitter Metabolites & Brain Health:
5-Hydroxyindolacetate (5HIAA), Dihydroxyphenylacetic (DOPAC), Homovanillic Acid (HVA), Homogentisic Homovanillic Acid, Vanillmandelic Acid (VMA), HVA : VMA Ratio, Quinolinic, Kynurenic, Thymine, Uracil
Vitamin & Nutrient Markers:
Ascorbic (Vitamin C), Pantothenic (Vitamin B5), Pyridoxic (Vitamin B6), Methylmalonic (Vitamin B12), Methylcitric (Vitamin H – Biotin), Glutaric (Vitamin B2 – Riboflavin), 3-Hydroxy-3-methylglutaric (CoQ10)
Detoxification & Antioxidant Pathways:
Pyroglutamic, Oxalic, Glycolic, Glyceric, Sebacic, Suberic, Hippuric, Mandelic, Ethylmalonic, Orotic, Carboxycitric, Phosphoric, Beta-Hydroxybutyric (3-Hydroxybutyric), Acetoacetic, 4-Hydroxybutyric, N-Acetylcysteine (Glutathione precursor)
Gut Microbial & Dysbiosis Markers:
3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA – Clostridia marker), 4-Cresol (C. difficile), Arabinose, DHPPA (Beneficial bacteria), 2-Hydroxyphenylacetic, 4-Hydroxyphenyllactic, 4-Hydroxyhippuric, 4-Hydroxybenzoic, Furan-2,5-dicarboxylic, 5-Hydroxymethyl-2-furoic, Tricarballylic, Indican, Tartaric, Citramalic
Fatty Acid & Organic Acid Metabolism:
Adipic, Suberic, Sebacic, Methylcitric, Methylsuccinic, Beta-Hydroxybutyric, Acetoacetic
Other Key Markers:
Creatinine (normalisation/reference marker), Orotic, Phosphoric
Clinical Use
The Organic Acids Test (OAT) provides a comprehensive analysis of 76 urinary metabolites, offering valuable insights into metabolic function, nutrient status, and underlying contributors to chronic health conditions. By measuring by-products of metabolism, this test helps uncover:
Nutritional deficiencies (e.g. B vitamins, antioxidants, amino acids)
Mitochondrial dysfunction and energy production issues
Impaired detoxification pathways
Neurotransmitter imbalances
Oxidative stress
Yeast and bacterial overgrowth in the gut
Urine is the preferred specimen for organic acids testing due to the higher concentration of metabolites, making this a highly sensitive and non-invasive assessment of biochemical pathways.
When to Consider This Test
Consider the Organic Acids Test for individuals experiencing:
Digestive concerns such as bloating, IBS, or suspected dysbiosis
Chronic fatigue or low energy
Mood disorders, anxiety, or poor stress resilience
Cognitive issues such as brain fog or memory decline
Blood sugar dysregulation or metabolic syndrome
Persistent inflammation or poor detox capacity
General health optimisation and personalised functional support
This test is particularly helpful in guiding targeted, evidence-based interventions. Results are delivered with graphical summaries and clinician-friendly interpretations, supporting clear treatment planning.
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Tested Biomarkers
3-Methylhistidine
Alanine
𝛼-Amino-N-butyrate
Ammonia
Anserine
Arginine
Asparagine
β-Alanine
Carnosine
Clinical use: Urinary amino acid (AA) analysis is vital for evaluating dietary protein intake, gastrointestinal function, and metabolic disorders. This test offers insights into nutrient deficiencies, organ health, and susceptibility to inflammation and oxidative stress. It aids in diagnosing and managing conditions related to amino acid metabolism.
When should you consider this test?
Consider amino acid analysis to assess dietary protein adequacy, gastrointestinal function, and various disorders affecting metabolism, aiding diagnosis and treatment. This test is useful for patients with ADD/ADHD, Depression and Anxiety, Digestive Disorders, Insomnia, Kidney Function, Nutritional Deficiencies, Rheumatoid Arthritis and more.
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Biomarkers Analyzed:
Amino acids
Organic acids
Fatty acids
Oxidative stress markers
Clinical Use: Provides a comprehensive nutritional and metabolic assessment, guiding personalized dietary and supplement interventions to optimize health.
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Our Microbiome Tests
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Biomarkers Analyzed:
Commensal Bacteria
Pathogenic Bacteria
Opportunistic Pathogens
Fungi/Yeast
Parasites
Inflammatory Markers (e.g., Calprotectin)
Digestive Markers (e.g., Elastase)
Immune Markers (e.g., Secretory IgA)
Clinical Use: Evaluates the gastrointestinal microbiome, digestion, absorption, inflammation, and infection to assess gut health and guide treatment strategies.
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Biomarkers Analyzed:
All Markers in GI 360
Zonulin
Helicobacter pylori Antigens
Clinical Use: Expands upon the GI 360 by assessing intestinal permeability (leaky gut) through zonulin levels and detecting H. pylori infection, which is associated with ulcers and gastritis.
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